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        Journal Of Medicinal Chemistry

        Journal Of Medicinal ChemistrySCIE

        國際簡稱:J. Med. Chem.  參考譯名:藥物化學(xué)雜志

        • 中科院分區(qū)

          1區(qū)

        • CiteScore分區(qū)

          Q1

        • JCR分區(qū)

          Q1

        基本信息:
        ISSN:0022-2623
        E-ISSN:1520-4804
        是否OA:開放
        是否預(yù)警:否
        TOP期刊:是
        出版信息:
        出版地區(qū):UNITED STATES
        出版商:American Chemical Society
        出版語言:English
        出版周期:Biweekly
        出版年份:1959
        研究方向:醫(yī)學(xué)-醫(yī)藥化學(xué)
        評價信息:
        影響因子:6.8
        H-index:240
        CiteScore指數(shù):12.8
        SJR指數(shù):1.986
        SNIP指數(shù):1.594
        發(fā)文數(shù)據(jù):
        Gold OA文章占比:13.77%
        研究類文章占比:98.81%
        年發(fā)文量:922
        自引率:0.1095...
        開源占比:0.099
        出版撤稿占比:0.0011...
        出版國人文章占比:0.14
        OA被引用占比:0.0691...
        英文簡介 期刊介紹 CiteScore數(shù)據(jù) 中科院SCI分區(qū) JCR分區(qū) 發(fā)文數(shù)據(jù) 常見問題

        英文簡介Journal Of Medicinal Chemistry期刊介紹

        The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.

        Some specific areas that are appropriate include the following:

        * Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools.

        * Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.

        *Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds.

        * Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition.

        *Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge.

        * Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules.

        * Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs.

        * Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.

        期刊簡介Journal Of Medicinal Chemistry期刊介紹

        《Journal Of Medicinal Chemistry》自1959出版以來,是一本醫(yī)學(xué)優(yōu)秀雜志。致力于發(fā)表原創(chuàng)科學(xué)研究結(jié)果,并為醫(yī)學(xué)各個領(lǐng)域的原創(chuàng)研究提供一個展示平臺,以促進(jìn)醫(yī)學(xué)領(lǐng)域的的進(jìn)步。該刊鼓勵先進(jìn)的、清晰的闡述,從廣泛的視角提供當(dāng)前感興趣的研究主題的新見解,或?qū)彶槎嗄陙砟硞€重要領(lǐng)域的所有重要發(fā)展。該期刊特色在于及時報道醫(yī)學(xué)領(lǐng)域的最新進(jìn)展和新發(fā)現(xiàn)新突破等。該刊近一年未被列入預(yù)警期刊名單,目前已被權(quán)威數(shù)據(jù)庫SCIE收錄,得到了廣泛的認(rèn)可。

        該期刊投稿重要關(guān)注點:

        Cite Score數(shù)據(jù)(2024年最新版)Journal Of Medicinal Chemistry Cite Score數(shù)據(jù)

        • CiteScore:12.8
        • SJR:1.986
        • SNIP:1.594
        學(xué)科類別 分區(qū) 排名 百分位
        大類:Pharmacology, Toxicology and Pharmaceutics 小類:Drug Discovery Q1 13 / 157

        92%

        大類:Pharmacology, Toxicology and Pharmaceutics 小類:Molecular Medicine Q1 24 / 178

        86%

        CiteScore 是由Elsevier(愛思唯爾)推出的另一種評價期刊影響力的文獻(xiàn)計量指標(biāo)。反映出一家期刊近期發(fā)表論文的年篇均引用次數(shù)。CiteScore以Scopus數(shù)據(jù)庫中收集的引文為基礎(chǔ),針對的是前四年發(fā)表的論文的引文。CiteScore的意義在于,它可以為學(xué)術(shù)界提供一種新的、更全面、更客觀地評價期刊影響力的方法,而不僅僅是通過影響因子(IF)這一單一指標(biāo)來評價。

        歷年Cite Score趨勢圖

        中科院SCI分區(qū)Journal Of Medicinal Chemistry 中科院分區(qū)

        中科院 2023年12月升級版 綜述期刊:否 Top期刊:是
        大類學(xué)科 分區(qū) 小類學(xué)科 分區(qū)
        醫(yī)學(xué) 1區(qū) CHEMISTRY, MEDICINAL 藥物化學(xué) 1區(qū)

        中科院分區(qū)表 是以客觀數(shù)據(jù)為基礎(chǔ),運用科學(xué)計量學(xué)方法對國際、國內(nèi)學(xué)術(shù)期刊依據(jù)影響力進(jìn)行等級劃分的期刊評價標(biāo)準(zhǔn)。它為我國科研、教育機(jī)構(gòu)的管理人員、科研工作者提供了一份評價國際學(xué)術(shù)期刊影響力的參考數(shù)據(jù),得到了全國各地高校、科研機(jī)構(gòu)的廣泛認(rèn)可。

        中科院分區(qū)表 將所有期刊按照一定指標(biāo)劃分為1區(qū)、2區(qū)、3區(qū)、4區(qū)四個層次,類似于“優(yōu)、良、及格”等。最開始,這個分區(qū)只是為了方便圖書管理及圖書情報領(lǐng)域的研究和期刊評估。之后中科院分區(qū)逐步發(fā)展成為了一種評價學(xué)術(shù)期刊質(zhì)量的重要工具。

        歷年中科院分區(qū)趨勢圖

        JCR分區(qū)Journal Of Medicinal Chemistry JCR分區(qū)

        2023-2024 年最新版
        按JIF指標(biāo)學(xué)科分區(qū) 收錄子集 分區(qū) 排名 百分位
        學(xué)科:CHEMISTRY, MEDICINAL SCIE Q1 4 / 72

        95.1%

        按JCI指標(biāo)學(xué)科分區(qū) 收錄子集 分區(qū) 排名 百分位
        學(xué)科:CHEMISTRY, MEDICINAL SCIE Q1 1 / 72

        99.31%

        JCR分區(qū)的優(yōu)勢在于它可以幫助讀者對學(xué)術(shù)文獻(xiàn)質(zhì)量進(jìn)行評估。不同學(xué)科的文章引用量可能存在較大的差異,此時單獨依靠影響因子(IF)評價期刊的質(zhì)量可能是存在一定問題的。因此,JCR將期刊按照學(xué)科門類和影響因子分為不同的分區(qū),這樣讀者可以根據(jù)自己的研究領(lǐng)域和需求選擇合適的期刊。

        歷年影響因子趨勢圖

        發(fā)文數(shù)據(jù)

        2023-2024 年國家/地區(qū)發(fā)文量統(tǒng)計
        • 國家/地區(qū)數(shù)量
        • USA1072
        • CHINA MAINLAND529
        • GERMANY (FED REP GER)292
        • England275
        • Italy188
        • France145
        • Switzerland116
        • Spain115
        • Australia100
        • Canada97

        本刊中國學(xué)者近年發(fā)表論文

        • 1、Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small- cell Lung Cancer

          Author: Pei, Junping; Wang, Guan; Wang, Aoxue; Wu, Chengyong; Pan, Xiaoli; Shuai, Wen; Bu, Faqian; Zhu, Yumeng; Wang, Yuxi; Ouyang, Liang; Li, Weimin

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acs.jmedchem.3c00027

        • 2、Discovery of Pyridinone Derivatives as Potent, Selective, and Orally Bioavailable Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

          Author: Zhu, Chenyu; Ze, Shuyin; Zhou, Ronghui; Yang, Xinyu; Wang, Haojie; Chai, Xiaolei; Fang, Meimiao; Liu, Mingyao; Wang, Yonghui; Lu, Weiqiang; Xie, Qiong

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4734-4754. DOI: 10.1021/acs.jmedchem.2c018604734J

        • 3、Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway

          Author: Zhang, Xinqi; Han, Qianyu; Hou, Ruilin; Xu, Lijuan; Zhang, Wannian; Xing, Chengguo; Xue, Lei; Zhuang, Chunlin

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 5261-5278. DOI: 10.1021/acs.jmedchem.3c00197

        • 4、Application and Study of ROCK Inhibitors in Pulmonary Fibrosis: Recent Developments and Future Perspectives

          Author: Xie, Yuting; Yue, Lin; Shi, Yaojie; Su, Xingping; Gan, Cailing; Liu, Hongyao; Xue, Taixiong; Ye, Tinghong

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4342-4360. DOI: 10.1021/acs.jmedchem.2c01753

        • 5、Development of Son of Sevenless Homologue 1 (SOS1) Modulators To Treat Cancers by Regulating RAS Signaling

          Author: Luo, Guangmei; Wang, Bingrui; Hou, Qiangqiang; Wu, Xiaoxing

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4324-4341. DOI: 10.1021/acs.jmedchem.2c01729

        • 6、Unsymmetrical Phosphodiesters as GPR84 Antagonists with High Blood Exposure for the Treatment of Lung Inflammation

          Author: Li, Shao-Xian; Wang, Si-Wei; Chen, Lin-Hai; Zhang, Qing; Lu, Dan; Chen, Jing; Fang, You-Chen; Gu, Min; Xie, Xin; Nan, Fa-Jun

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 8, pp. 5820-5838. DOI: 10.1021/acs.jmedchem.3c00053

        • 7、Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1

          Author: Gallego, Rebecca A.; Bernier, Louise; Chen, Hui; Cho-Schultz, Sujin; Chung, Loanne; Collins, Michael; Del Bel, Matthew; Elleraas, Jeff; Jones, Cinthia Costa; Cronin, Ciaran N.; Edwards, Martin; Fang, Xu; Fisher, Timothy; He, Mingying; Hoffman, Jacqui; Huo, Ruiduan; Jalaie, Mehran; Johnson, Eric; Johnson, Ted W.; Kania, Robert S.; Kraus, Manfred; Lafontaine, Jennifer; Le, Phuong; Liu, Tongnan; Maestre, Michael; Matthews, Jean; McTigue, Michele; Miller, Nichol; Mu, Qiming; Qin, Xulong; Ren, Shijian; Richardson, Paul; Rohner, Allison; Sach, Neal; Shao, Li; Smith, Graham; Su, Ruirui; Sun, Bin; Timofeevski, Sergei; Tran, Phuong; Wang, Shuiwang; Wang, Wei; Zhou, Ru; Zhu, Jinjiang; Nair, Sajiv K.

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4888-4909. DOI: 10.1021/acs.jmedchem.2c02038

        • 8、Exploration of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Bispecific Inhibitors Based on the Moiety of Fedratinib for Treatment of Both Hematologic Malignancies and Solid Cancers

          Author: Qiu, Qianqian; Chi, Fanglian; Zhou, Daoguang; Xie, Zhancheng; Liu, Yunxiao; Wu, Hanyu; Yin, Ziyu; Shi, Wei; Qian, Hai

          Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acs.jmedchem.3c00036

        投稿常見問題

        通訊方式:AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036。

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